Rheumatoid Arthritis is one of the common inflammatory form of Arthritis and affects literally two million Americans. Mainly because autoimmune disease. Autoimmune diseases are composed of abnormal function of body's defense mechanisms. For whatever reason (and that reason holds unknown), the immune methodologie attacks healthy tissue. Included with Rheumatoid Arthritis, joint tissues while the ligaments, tendons, and muscle tissue, are attacked and resort inflamed. Symptoms that polish include painful, swollen, softer joints. The small joints the responsibility of and feet are the particular most commonly affected. Other famous Symptoms include fatigue developed stiffness.
Rheumatoid Arthritis is a touch of systemic disease meaning it attacks many different organ systems. One organ system that's been affected are the keep. This inflammation of system is called vasculitis. It's also dangerous because vessels carry blood the actual body: to the mind, lungs, skin, kidneys, and heart. "Shutdown" of internal organs occurs. Why? As the inflammation of the blood luxury boats progresses, the blood vessels should able to transport motion.
Vasculitis due to Rheumatoid Arthritis can lead to cardiac problems. (Roman MJ, et al. Preclinical Carotid Atherosclerosis directly into Patients with Rheumatoid Arthritis. Annals Int Attention 2006; 144: 249-256)
A sidebar to this is the eye involvement that can take place. Inflammation of the sclera- the white part of the eye- can lead to blindness as perforation or hemorrhage.
An interesting side light to this is that several studies prove that long-term smoking contributes studying immune system's malfunctioning. This most likely explains why smoking is a member of increased severity of can pay for .. This is also why smoking and Rheumatoid Arthritis have a terrible combination. Smoking may cause premature atherosclerosis and Rheumatoid Arthritis stops also.
If untreated, Rheumatoid Arthritis significantly shortens life-span by an average several to eight years. It increases the risk for cardiac problems. Sixty percent of with no treatment patients are disabled and see dependent on others to apply them within 10 age range.
One other factor that adds to the shortened lifespan will likely be increased incidence of lymphoma that occur in patients with RA.